NFL
Detroit Lions
vs
Buffalo Bills
Thursday, September 17, 2026 at 8:15 PM EDT
2d 23h
Moneyline
Detroit Lions +180.00 BetRivers
Buffalo Bills -205.00 DraftKings
Total
Over 53.50 -110.00 BetMGM
Under 53.50 -108.00 BetMGM
Spread
Detroit Lions +4.50 -110.00 BetMGM
Buffalo Bills -4.50 -108.00 BetMGM

Moneyline

Sportsbook Detroit Lions Buffalo Bills
BetMGM +175.00 -210.00
BetRivers +180.00 -225.00
DraftKings +170.00 -205.00
Fanatics +175.00 -215.00
FanDuel +180.00 -215.00
Caesars +180.00 -218.00

Spread

Sportsbook Detroit Lions Buffalo Bills
BetMGM +4.50 (-110.00) -4.50 (-108.00)
BetRivers +4.00 (-107.00) -4.00 (-114.00)
DraftKings +4.50 (-112.00) -4.50 (-108.00)
Fanatics +4.50 (-110.00) -4.50 (-110.00)
FanDuel +4.50 (-115.00) -4.50 (-105.00)
Caesars +4.50 (-113.00) -4.50 (-106.00)

Total

Sportsbook Over Under
BetMGM 53.50 (-110.00) 53.50 (-108.00)
BetRivers 53.50 (-108.00) 53.50 (-113.00)
DraftKings 53.50 (-115.00) 53.50 (-105.00)
Fanatics 53.50 (-110.00) 53.50 (-110.00)
FanDuel 53.50 (-115.00) 53.50 (-105.00)
Caesars 53.50 (-112.00) 53.50 (-109.00)
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